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Anaphylaxis after antibiotic — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyAnaphylaxis after antibioticGPhC CRA

A patient reports wheeze, facial swelling and collapse after taking the first dose of co-amoxiclav. They are now well after ambulance treatment. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Record penicillin allergy and advise avoidance pending specialist review

The reaction is consistent with severe immediate beta-lactam allergy. Accurate documentation and patient counselling are essential to prevent recurrence. In this scenario, the correct option is record penicillin allergy and advise avoidance pending specialist review. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS