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NSAID renal risk — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsNSAID renal riskGPhC CRA

An older patient with CKD stage 3 and heart failure asks to buy ibuprofen for knee pain. They take ramipril and furosemide. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Avoid NSAID and recommend safer analgesia or referral

NSAIDs can worsen renal function and heart failure, especially with ACE inhibitors and diuretics. The combination increases acute kidney injury risk. In this scenario, the correct option is avoid NSAID and recommend safer analgesia or referral. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS