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ACE inhibitor angioedema — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A patient taking ramipril for three months presents with lip swelling but no rash. They asks for an antihistamine. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Refer urgently and advise ramipril should be reviewed

ACE inhibitor angioedema can occur without urticaria and may threaten the airway. Urgent assessment and prescriber review are required. In this scenario, the correct option is refer urgently and advise ramipril should be reviewed. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS