Lactulose hepatic encephalopathy — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentLactulose hepatic encephalopathyGPhC CRA

During an independent infusion check, dopamine is prescribed at 5 micrograms/kg/minute for a 70 kg patient. The prepared syringe label states 200 mg in a final volume of 250 mL. Which pump-rate entry should be accepted?

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Correct answer: E — 26.25 mL/hour

Dose = 5 × 70 = 350 micrograms/minute = 21 mg/hour. Concentration = 200 mg/250 mL = 0.8 mg/mL. Rate = 21/0.8 = 26.25 mL/hour, Option E. Option C omits conversion to hourly dose. Option D halves the required dose. Option B treats mg/hour as mL/hour. Option A rounds before completing the calculation.

Reference: GPhC Common Registration Assessment framework 2026: https://assets.pharmacyregulation.org/files/2025-09/Common-Registration-Assessment-framework-for-sittings-in-2026.pdf