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AF rate-control worsening asthma — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsAF rate-control worsening asthmaGPhC CRA

A patient with asthma is prescribed propranolol for palpitations. Their asthma has recently needed salbutamol several times each week. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EBronchospasm and loss of beta-agonist effect

Non-selective beta-blockers can worsen asthma and reduce response to beta-agonists. This should be queried before supply in a symptomatic patient. In this scenario, the correct option is bronchospasm and loss of beta-agonist effect. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; Stockley's Drug Interactions