AF rate-control worsening asthma — GPhC CRA MCQ
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Correct answer: E — Bronchospasm and loss of beta-agonist effect
Non-selective beta-blockers can worsen asthma and reduce response to beta-agonists. This should be queried before supply in a symptomatic patient. In this scenario, the correct option is bronchospasm and loss of beta-agonist effect. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.
Reference: BNF; Stockley's Drug Interactions