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Aminoglycoside ototoxicity — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyAminoglycoside ototoxicityGPhC CRA

A patient receiving gentamicin reports new tinnitus and dizziness. The next dose is due this evening in a community hospital. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AWithhold and refer urgently for level and clinical review

Gentamicin can cause ototoxicity and nephrotoxicity. New tinnitus or vestibular symptoms require urgent review before further dosing. In this scenario, the correct option is withhold and refer urgently for level and clinical review. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF