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Statin muscle symptoms — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyStatin muscle symptomsGPhC CRA

A patient taking atorvastatin 80 mg develops severe muscle pain, weakness and dark urine after starting an interacting antibiotic. What is the most appropriate action?

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Correct answer: D — Refer urgently for assessment including creatine kinase and renal function

Severe muscle symptoms with dark urine suggest possible rhabdomyolysis and require urgent assessment. This makes refer urgently for assessment including creatine kinase and renal function the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF; NICE CKS