IBS antispasmodic counselling — GPhC CRA MCQ
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Correct answer: D — Take standard mebeverine 20 minutes before each main meal
Take standard mebeverine 20 minutes before each main meal: Mebeverine is conventionally taken before meals so its antispasmodic effect coincides with predictable post-prandial symptoms. Take standard-release mebeverine immediately after each main meal: Standard counselling is to take it before meals, not routinely after them. Take the full daily mebeverine dose together at bedtime: Combining doses is not the prescribed schedule and can increase adverse effects. Take mebeverine after each loose stool as an antimotility dose: Mebeverine is an antispasmodic, not a rescue antimotility agent. Crush modified-release mebeverine into food before each main meal: Modified-release dosage forms should not be crushed and this is not the product specified.
Reference: BNF: mebeverine hydrochloride: https://bnf.nice.org.uk/drugs/mebeverine-hydrochloride/