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Gabapentin renal dose adjustment — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentGabapentin renal dose adjustmentGPhC CRA

A 78-year-old taking gabapentin 600 mg three times daily becomes confused after an acute kidney injury. What is the most appropriate action?

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Correct answer: A — Review gabapentin dose because renal clearance is reduced

Gabapentin is renally cleared and accumulation can cause CNS adverse effects in renal impairment. This makes review gabapentin dose because renal clearance is reduced the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF