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Allopurinol severe rash — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsAllopurinol severe rashGPhC CRA

A patient started allopurinol 3 weeks ago and now has widespread rash, fever and facial swelling. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Advise urgent medical assessment and stop pending review

Allopurinol can rarely cause severe hypersensitivity reactions, especially with systemic symptoms. This makes advise urgent medical assessment and stop pending review the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF; NICE CKS