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Folic acid with methotrexate — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsFolic acid with methotrexateGPhC CRA

A patient starts weekly methotrexate for rheumatoid arthritis and is also prescribed folic acid. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — It reduces methotrexate adverse effects and should be taken as prescribed

Folic acid is used with low-dose methotrexate to reduce adverse effects while maintaining treatment. This makes it reduces methotrexate adverse effects and should be taken as prescribed the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF; NICE CKS