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Spironolactone renal impairment — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentSpironolactone renal impairmentGPhC CRA

A heart failure patient with eGFR 26 and potassium 5.3 mmol/L presents a new prescription for spironolactone. What is the most appropriate action?

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Correct answer: C — Contact the prescriber before supply

Spironolactone can cause dangerous hyperkalaemia, particularly with reduced eGFR and raised potassium. This makes contact the prescriber before supply the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF; NICE CKS