skip to main content

Lithium and ACE inhibitor — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardDrug InteractionsLithium and ACE inhibitorGPhC CRA

A patient stable on lithium is newly prescribed lisinopril and has borderline renal function. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — ACE inhibitors can increase lithium levels

ACE inhibitors can reduce lithium clearance and increase toxicity risk, especially with renal impairment. This makes ace inhibitors can increase lithium levels the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions