COPD infective exacerbation — GPhC CRA MCQ
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Correct answer: D — Amoxicillin 500 mg three times daily
Purulent sputum during COPD exacerbation supports antibacterial treatment, and amoxicillin is a usual first-line option when suitable. This makes amoxicillin 500 mg three times daily the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.
Reference: NICE CKS; BNF