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UTI renal impairment nitrofurantoin — GPhC CRA MCQ

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ModerateInfectionsUTI renal impairment nitrofurantoinGPhC CRA

A 79-year-old woman with lower UTI symptoms has eGFR 28 and a prescription for nitrofurantoin MR 100 mg twice daily. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Discuss a non-nitrofurantoin antibiotic with the prescriber

Nitrofurantoin may be unsuitable when renal function is reduced, so the prescriber should choose a safer antibiotic. This makes discuss a non-nitrofurantoin antibiotic with the prescriber the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF; NICE CKS