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NSAID with anticoagulant — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsNSAID with anticoagulantGPhC CRA

A patient taking apixaban for AF asks for naproxen for back pain and has previous dyspepsia. What is the most important interaction to flag?

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Correct answer: BIncreased bleeding risk

NSAIDs increase GI and overall bleeding risk when combined with anticoagulants such as apixaban. This makes increased bleeding risk the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions