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Prednisolone and NSAID gastric risk — GPhC CRA MCQ

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EasyEndocrine TherapeuticsPrednisolone and NSAID gastric riskGPhC CRA

A patient taking prednisolone for ulcerative colitis asks to buy naproxen and has a previous peptic ulcer. What is the most appropriate alternative?

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Correct answer: D — Recommend paracetamol and refer for analgesia review

Systemic corticosteroids plus NSAIDs increase gastrointestinal harm, so a safer analgesic approach is preferred. This makes recommend paracetamol and refer for analgesia review the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions