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Fluconazole and warfarin — GPhC CRA MCQ

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HardInfectionsFluconazole and warfarinGPhC CRA

A patient taking warfarin asks to buy fluconazole 150 mg; INR was 3.0 last week and they report bruising. What is the most important interaction to flag?

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Correct answer: B — Increased anticoagulant effect and bleeding risk

Fluconazole can increase warfarin effect and the patient already reports bruising. This makes increased anticoagulant effect and bleeding risk the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions