QT prolongation with amiodarone — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsQT prolongation with amiodaroneGPhC CRA

A man taking amiodarone is prescribed erythromycin; he has previous syncope and low potassium. What is the most important interaction to flag?

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Correct answer: D — Additive QT prolongation and arrhythmia risk

Amiodarone and macrolides can prolong the QT interval, and hypokalaemia increases arrhythmia risk. This makes additive qt prolongation and arrhythmia risk the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions