skip to main content

Depression SSRI initiation — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsDepression SSRI initiationGPhC CRA

A 34-year-old man with moderate depression agrees to medicine treatment; he has no relevant comorbidities and takes no medicines. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Start sertraline once daily

An SSRI such as sertraline is a usual first-line antidepressant choice when medicine treatment is appropriate. This makes start sertraline once daily the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: NICE CKS; BNF