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Carbimazole agranulocytosis — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsCarbimazole agranulocytosisGPhC CRA

A woman taking carbimazole for Graves' disease presents with sore throat, fever and mouth ulcers. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AArrange an urgent full blood count

Sore throat and fever on carbimazole may indicate agranulocytosis, requiring urgent blood count assessment. This makes arrange an urgent full blood count the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF