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Lithium and NSAID — GPhC CRA MCQ

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EasyCNS TherapeuticsLithium and NSAIDGPhC CRA

A patient stabilised on lithium asks to buy ibuprofen while mildly dehydrated after vomiting yesterday. What is the most important interaction to flag?

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Correct answer: C — Ibuprofen may increase lithium levels and toxicity risk

NSAIDs can increase lithium levels, and dehydration further increases toxicity risk. This makes ibuprofen may increase lithium levels and toxicity risk the single best answer in this scenario. The other options would either miss the key safety issue, delay appropriate review, or fail to meet the relevant clinical or professional requirement.

Reference: BNF interactions