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PPI review — GPhC CRA MCQ

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EasyGastro-intestinal TherapeuticsPPI reviewGPhC CRA

A 58-year-old man asks to continue omeprazole 20mg daily that he started after a short course of naproxen. The NSAID has now stopped and his reflux symptoms are mild and infrequent. What is the most appropriate alternative?

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Correct answer: E — Discuss step-down or stopping if symptoms remain controlled

PPIs are effective but long-term use should be reviewed and stepped down where appropriate. If the original indication has ended and symptoms are mild, reducing dose, on-demand use or stopping may be considered. Alarm symptoms such as dysphagia, weight loss or gastrointestinal bleeding would require referral.

Reference: NICE CKS; BNF