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Clozapine neutropenia — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyClozapine neutropeniaGPhC CRA

A patient taking clozapine phones the pharmacy with fever, sore throat and mouth ulcers. They are due to collect the next supply today. The clozapine monitoring service normally sends blood results to the pharmacy. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Check urgent blood monitoring status and refer for possible neutropenia

Clozapine can cause neutropenia and agranulocytosis, and symptoms such as fever or sore throat require urgent assessment. Supply is linked to mandatory blood monitoring arrangements. The pharmacist should follow the clozapine monitoring service process and refer urgently.

Reference: BNF; clozapine monitoring service guidance