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LMWH in renal impairment — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentLMWH in renal impairmentGPhC CRA

A 75-year-old woman with eGFR 21mL/min/1.73m2 is prescribed enoxaparin treatment dose for suspected deep vein thrombosis. The dose appears to be the standard dose for normal renal function. What is the most appropriate action?

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Correct answer: C — Query dose adjustment because low molecular weight heparins accumulate in renal impairment

Low molecular weight heparins can accumulate in significant renal impairment, increasing bleeding risk. Treatment dosing should be reviewed using renal function, weight and indication. The pharmacist should clarify the intended dose before supply.

Reference: BNF