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SGLT2 inhibitor perioperative advice — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsSGLT2 inhibitor perioperative adviceGPhC CRA

A 45-year-old man with type 2 diabetes takes canagliflozin. He is admitted for elective surgery next week and asks whether his diabetes medicines need review before the procedure. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdvise prescriber review because SGLT2 inhibitors are usually withheld around surgery

SGLT2 inhibitors are commonly withheld around major surgery or acute illness to reduce ketoacidosis risk. The patient needs an individual perioperative plan from the surgical or diabetes team. The pharmacist should ensure he knows when to restart and what symptoms require urgent review.

Reference: BNF; MHRA Drug Safety Update