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Digoxin and verapamil — GPhC CRA MCQ

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HardDrug InteractionsDigoxin and verapamilGPhC CRA

A 73-year-old man takes digoxin for atrial fibrillation and is prescribed verapamil for rate control. He reports nausea and his pulse is 48 beats/min. What is the most important interaction to flag?

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Correct answer: E — Verapamil can increase digoxin levels and bradycardia risk

Verapamil can increase digoxin concentrations and both medicines can contribute to bradycardia. Nausea and a pulse of 48 beats/min are concerning for toxicity or excessive rate control. The prescription should be queried urgently and the patient assessed.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-51