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Osteoarthritis analgesia — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsOsteoarthritis analgesiaGPhC CRA

A 60-year-old man with hand osteoarthritis asks for an analgesic. He takes apixaban and has a previous gastric ulcer. His pain is localised to two finger joints. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Suggest topical NSAID with caution and discuss non-drug measures

Topical NSAIDs may provide local benefit with lower systemic exposure than oral NSAIDs, though caution remains. Oral NSAIDs would increase bleeding and gastrointestinal risk in a patient taking apixaban with previous ulcer disease. Non-drug measures and paracetamol may also be discussed depending on suitability.

Reference: BNF; NICE CKS