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Hyperkalaemia — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyHyperkalaemiaGPhC CRA

A 64-year-old man takes spironolactone and ramipril. He complains of muscle weakness and palpitations after starting a potassium salt substitute. His eGFR is 39mL/min/1.73m2. What monitoring is required?

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Correct answer: B — Check serum potassium and renal function urgently

Spironolactone, ACE inhibitors, CKD and potassium salt substitutes all increase hyperkalaemia risk. Muscle weakness and palpitations may be symptoms of clinically significant hyperkalaemia. Urgent potassium and renal function assessment is required.

Reference: BNF; NICE CKS