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Penicillin allergy — GPhC CRA MCQ

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ModerateInfectionsPenicillin allergyGPhC CRA

A 28-year-old woman reports a previous immediate rash, lip swelling and wheeze after amoxicillin. She is now prescribed phenoxymethylpenicillin for tonsillitis. She is otherwise well. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Contact the prescriber to request a non-penicillin antibiotic if treatment is needed

Lip swelling and wheeze after amoxicillin suggest a possible immediate hypersensitivity reaction. Phenoxymethylpenicillin is another penicillin and should be avoided unless allergy assessment has clarified safety. The pharmacist should contact the prescriber for an appropriate alternative if antibiotics are indicated.

Reference: BNF; NICE CKS