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ACE inhibitor angioedema — GPhC CRA MCQ

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EasyAdverse Drug Reactions and SafetyACE inhibitor angioedemaGPhC CRA

A 59-year-old man taking ramipril develops sudden swelling of the lips and tongue with a hoarse voice. He started ramipril three months ago and has no rash. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Arrange emergency care for suspected ACE inhibitor angioedema

ACE inhibitors can cause angioedema, which may occur even after months of treatment. Tongue swelling and hoarseness suggest potential airway involvement and require emergency assessment. The ACE inhibitor should not be continued without medical review.

Reference: BNF; NICE CKS