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GLP-1 receptor agonist pancreatitis — GPhC CRA MCQ

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HardEndocrine TherapeuticsGLP-1 receptor agonist pancreatitisGPhC CRA

A 49-year-old woman started semaglutide two months ago. She reports persistent severe abdominal pain radiating to her back with vomiting. She has lost weight and has no diarrhoea. What is the most appropriate action?

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Correct answer: D — Refer urgently because pancreatitis needs assessment

GLP-1 receptor agonists can cause gastrointestinal adverse effects, but severe persistent abdominal pain radiating to the back raises concern for pancreatitis. This requires urgent clinical assessment. The medicine should not simply be continued without review.

Reference: BNF; NICE CKS