Valproate pregnancy prevention — GPhC CRA MCQ
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Correct answer: E — Refer to her specialist urgently to review valproate and pregnancy prevention requirements
Valproate is highly teratogenic and is subject to strict pregnancy prevention and specialist review requirements. Stopping antiepileptic treatment abruptly can also be dangerous because of seizure risk. The pharmacist should refer urgently for specialist review and ensure the patient understands the need for effective contraception until reviewed.
Reference: MHRA Drug Safety Update; BNF