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Mesalazine monitoring — GPhC CRA MCQ

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ModerateGastro-intestinal TherapeuticsMesalazine monitoringGPhC CRA

A 36-year-old woman takes mesalazine modified-release tablets for ulcerative colitis. She reports new bruising and sore throat. Her last blood tests were more than a year ago. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EArrange urgent full blood count and prescriber review

Mesalazine can rarely cause blood dyscrasias and renal impairment. Sore throat and bruising are warning symptoms that need prompt full blood count and clinical review. Periodic renal function monitoring is also commonly required during longer-term treatment.

Reference: BNF; NICE CKS