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Alendronate administration — GPhC CRA MCQ

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EasyGastro-intestinal TherapeuticsAlendronate administrationGPhC CRA

A 69-year-old woman collecting alendronic acid 70mg tablets says she usually takes tablets with breakfast and then lies down because of back pain. She asks how to take the weekly tablet. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Take it with plain water on waking and remain upright before food

Alendronic acid can cause oesophageal irritation and has poor absorption. It should be taken with plain water on waking, with the patient remaining upright and delaying food, drink and other medicines according to instructions. Calcium, food and milk reduce absorption.

Reference: BNF; NICE CKS