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Ciclosporin and NSAIDs — GPhC CRA MCQ

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ModerateDrug InteractionsCiclosporin and NSAIDsGPhC CRA

A 46-year-old woman taking ciclosporin after renal transplant asks to buy ibuprofen for dental pain. Her creatinine has been stable but she has an appointment with her transplant team next month. What is the most important interaction to flag?

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Correct answer: A — NSAIDs can increase nephrotoxicity risk with ciclosporin

Ciclosporin is nephrotoxic and NSAIDs can further impair renal function. Dental pain requires dental assessment and a safer analgesic plan. The pharmacist should avoid selling ibuprofen without specialist or prescriber input.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-50