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Tacrolimus brand prescribing — GPhC CRA MCQ

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HardDispensing and SupplyTacrolimus brand prescribingGPhC CRA

A pharmacy receives a prescription for tacrolimus modified-release capsules. The patient's previous supply was a different brand and the patient is a transplant recipient. What is the most appropriate action?

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Correct answer: D — Maintain brand consistency or confirm any intended brand change with the specialist

Tacrolimus is a narrow therapeutic index medicine where brand consistency is important. Switching between formulations can alter exposure and risk rejection or toxicity. Any brand change should be intentional and supervised with appropriate monitoring.

Reference: BNF; MHRA safety advice