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Dual RAAS blockade — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsDual RAAS blockadeGPhC CRA

A 67-year-old man presents a discharge prescription for ramipril 5mg daily and losartan 50mg daily after admission with hypertension. His PMR shows both medicines are newly started. Potassium and renal function results are unavailable. What is the most appropriate action?

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Correct answer: E — Clarify with the prescriber before supplying dual RAAS blockade

Combining an ACE inhibitor with an ARB increases the risk of renal impairment, hypotension and hyperkalaemia and is generally avoided except under specialist direction. The absence of monitoring results increases concern. The pharmacist should clarify the intended regimen before supply.

Reference: BNF; NICE CKS