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Methotrexate folic acid — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsMethotrexate folic acidGPhC CRA

A 47-year-old man takes methotrexate once weekly and folic acid 5mg once weekly for psoriasis. He asks whether folic acid is necessary because it is not treating the skin directly. What would you advise the patient?

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Correct answer: B — Folic acid reduces methotrexate adverse effects and should be taken as prescribed

Folic acid is prescribed with low-dose methotrexate to reduce adverse effects such as mouth ulcers and gastrointestinal symptoms. It should be taken according to the prescriber's schedule, commonly on a different day from methotrexate. The patient should continue monitoring and report signs of toxicity.

Reference: BNF; NICE CKS