skip to main content

Formulation substitution — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateDispensing and SupplyFormulation substitutionGPhC CRA

A patient brings a prescription for sodium valproate oral solution. The pharmacy has tablets in stock but no liquid. The patient cannot swallow tablets and the dose is due today. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Source the correct formulation or contact the prescriber urgently

Formulation changes can alter dose delivery and suitability, especially for valproate. If the patient cannot swallow tablets, the correct formulation should be sourced or the prescriber contacted for a safe alternative. Missing antiepileptic doses can increase seizure risk.

Reference: BNF; MEP