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Lithium toxicity — GPhC CRA MCQ

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HardCNS TherapeuticsLithium toxicityGPhC CRA

A 44-year-old woman taking lithium carbonate modified-release reports vomiting and diarrhoea for 24 hours. She also feels shaky and unsteady. Her last lithium level was within range two months ago. What monitoring is required?

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Correct answer: C — Refer urgently for lithium level and clinical assessment

Vomiting, diarrhoea, tremor and ataxia can indicate lithium toxicity, and dehydration increases lithium levels. Urgent assessment and lithium level measurement are required. NSAIDs can increase lithium concentrations and should be avoided unless specifically advised.

Reference: BNF; NICE CKS