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DOAC renal dosing — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentDOAC renal dosingGPhC CRA

A 69-year-old woman with eGFR 26mL/min/1.73m2 is prescribed rivaroxaban 20mg once daily for atrial fibrillation. Her weight is 53kg and she has no recent bleeding. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: AQuery the dose because renal function affects DOAC dosing

Renal function is important when selecting and dosing DOACs. Rivaroxaban dose may need adjustment or alternative anticoagulation depending on indication and renal function. The pharmacist should clarify renal dosing before supply.

Reference: BNF; NICE CKS