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DOAC baseline monitoring — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsDOAC baseline monitoringGPhC CRA

A 74-year-old woman is newly prescribed edoxaban for atrial fibrillation. Her GP surgery asks what baseline information should be checked before issuing the first supply. She takes no interacting medicines. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ARenal function, liver function, full blood count and body weight

Before a DOAC is used, renal function, liver function, full blood count and body weight help guide dose suitability and bleeding risk assessment. Ongoing renal monitoring is particularly important in older people or renal impairment. Routine INR monitoring is not used to titrate edoxaban.

Reference: BNF; NICE CKS