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COPD triple therapy — GPhC CRA MCQ

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ModerateRespiratory TherapeuticsCOPD triple therapyGPhC CRA

A 71-year-old woman with COPD has had three infective exacerbations in the past year. She uses a LAMA/LABA inhaler regularly and has blood eosinophils raised on recent tests. Her prescriber asks about escalation. What is the most appropriate alternative?

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Correct answer: B — Consider adding inhaled corticosteroid as part of triple therapy

In COPD with recurrent exacerbations despite dual bronchodilation, inhaled corticosteroid as part of triple therapy may be appropriate, particularly with raised eosinophils or asthmatic features. Inhaler technique, adherence and smoking status should be reviewed. Long-term oral corticosteroids have significant toxicity and are not a routine preventive choice.

Reference: NICE CKS; BNF