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Hypertension first-line treatment — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension first-line treatmentGPhC CRA

A 45-year-old man of black African family origin has newly diagnosed hypertension. His clinic BP remains 158/98mmHg after ABPM confirmation. He has NKDA, eGFR >60mL/min/1.73m2 and HbA1c 38mmol/mol. What is the most appropriate alternative?

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Correct answer: D — Start amlodipine 5mg once daily

Calcium-channel blockers are preferred first-line antihypertensive treatment in adults of black African or African-Caribbean family origin without type 2 diabetes. ACE inhibitors can be less effective as first-line monotherapy in this group. The renal function and potassium do not create a contraindication, but they do not change the preferred first-line choice here.

Reference: NICE CKS; BNF