Methotrexate weekly dosing — GPhC CRA MCQ
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Correct answer: B — Stop supply until the dosing misunderstanding is resolved with urgent counselling and prescriber contact
Methotrexate dosing errors can be fatal, and it must be taken once weekly when prescribed for rheumatoid arthritis. Daily dosing is a serious misunderstanding requiring urgent intervention before supply. Counselling should confirm the weekly day, folic acid schedule, monitoring and toxicity symptoms.
Reference: BNF; MHRA safety advice