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Warfarin and NSAIDs — GPhC CRA MCQ

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EasyDrug InteractionsWarfarin and NSAIDsGPhC CRA

A 72-year-old woman taking warfarin asks to buy naproxen for shoulder pain. Her INR was 2.8 last week and she has a previous gastric ulcer. What is the most important interaction to flag?

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Correct answer: C — NSAIDs increase bleeding risk when taken with warfarin

NSAIDs increase gastrointestinal bleeding risk and can further increase harm in patients taking warfarin. Previous ulcer disease adds to the risk. Safer analgesic options and referral should be considered rather than selling naproxen.

Reference: BNF