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Paracetamol in low body weight — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentParacetamol in low body weightGPhC CRA

A frail 43 kg older woman is prescribed paracetamol 1 g four times daily after a fall. She has poor oral intake and drinks alcohol daily. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Query the dose because low body weight and risk factors may require dose reduction

Standard adult paracetamol dosing may be inappropriate in low body weight or hepatic risk factors. Chronic alcohol use and poor nutrition increase hepatotoxicity risk. The dose should be reviewed rather than supplied automatically.

Reference: BNF