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Methotrexate monitoring — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsMethotrexate monitoringGPhC CRA

A 50-year-old man starts methotrexate for psoriasis. He asks why the clinic keeps requesting blood tests. What monitoring is required?

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Correct answer: EFull blood count, liver function and renal function monitoring are required

Methotrexate can cause bone marrow suppression, hepatotoxicity and renal-related toxicity. Regular FBC, LFTs and renal function are standard monitoring. Folic acid reduces some adverse effects but does not remove monitoring requirements.

Reference: BNF