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Clozapine infection warning — GPhC CRA MCQ

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HardCNS TherapeuticsClozapine infection warningGPhC CRA

A patient taking clozapine asks for advice about fever, sore throat and mouth ulcers. He cannot contact the mental health team until tomorrow. What is the most appropriate action?

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Correct answer: A — Advise urgent same-day assessment and full blood count advice through clozapine monitoring arrangements

Clozapine can cause neutropenia or agranulocytosis, and infection symptoms require urgent assessment. Patients should know to report fever or sore throat promptly. Treatment changes must be coordinated with the clozapine monitoring service.

Reference: BNF